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KMID : 0860920130150010036
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2013 Volume.15 No. 1 p.36 ~ p.40
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Effect of Intramuscular Hydroxocobalamin for Carpal Tunnel Syndrome: Randomized Controlled Trial
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Yoon Kyung-Jae
Lee Yong-Taek
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Abstract
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Objectives: To evaluate the effect of intramuscular administration of hydroxocobalamine for the carpal tunnel syndrome (CTS) on clinical symptoms and electrophysiologic changes.
Subjects and Methods: 16 CTS patients were randomly assigned to hydroxocobalamine (HC) or sham group. HC group received intramuscular hydroxocobalamine (5 mg) 10 times for 20 days. Tinel score, Phalen time, Levin Questionnaire and nerve conduction study were measured 1 month after injection schedule. All patients were treated with ultrasound during trial period.
Results: Total six patients (three in each group) completed follow-up. After one month, Tinel score, Phalen time, Levin Questionnaire and nerve conduction study showed no significant difference between two groups.
Conclusion: Intramuscular hydroxocobalamin did not have beneficial effect on CTS for 1 month followup period. However, further data should be collected to conclude the effect of hydroxocobalamin on CTS.
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KEYWORD
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Carpal tunnel syndrome, Hydroxocobalamin, Vitamin B12
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